monogenic disease

1. There is an agreement that autosomal recessive juvenile parkinsonism ( AR-JP) is a monogenic disease caused by mutation in parkin gene.
   一致的观念认为常染色体隐性遗传性青少年型帕金森综合症（AR-JP）是parkin基因突变引起的一种单基因遗传病。
2. One Simple Method to Evaluate the Expected Maximum Lod Score of Monogenic Disease Pedigrees
   一种简便的预期最大LODSCORE值的推算方法
3. Based on the complex system, the study on identifying and mapping the disease genes developed more slowly than that on monogenic disease.
   基于这样一个复杂系统，各种复杂疾病的基因定位研究与单基因疾病相比进展非常缓慢。
4. It is also found that schizophrenia is not a monogenic disease, but probably a polygenic disease influenced by multiple genes with small or medium risks and by environment factors as well.
   另外研究也发现精神分裂症不是简单的单基因遗传病，而可能是多个微效或中效基因共同作用的多基因疾病，并且还受到环境因素的影响。

noun

1. an inherited disease controlled by a single pair of genes

   Synonym:    monogenic disorder